Nicolas Liaudet

Low-salt diet induces claudin-3 expression and drives adaptive changes in collecting duct of claudin-3-deficient mice

This study shows that a low-salt diet increases claudin-3 expression in mice, which reduces paracellular sodium permeability, and claudin-3-deficient mice adapt by upregulating other claudins and ENaC to maintain sodium balance.

CtBP1 coordinates synaptic, metabolic and contractile changes induced by denervation in skeletal muscle

Tissular glucocorticoid reactivating enzyme 11beta-HSD1 drives pathogenic myofibroblast differentiation in chronic kidney disease

This study identifies 11beta-HSD1 as a driver of myofibroblast differentiation in CKD, showing its inhibition reduces fibrosis and improves renal function.