BiophysicsbioRxivPreprint
Structural characterization of MAM01 and other cost-effective engineered monoclonal antibodies for malaria prevention
Monika Jain, Sashank Agrawal, Gonzalo Ernesto González-Páez…·Ian A. Wilson
The paper determines the crystal structures of engineered monoclonal antibodies MAM01 and MS-1805 in complex with Plasmodium falciparum CSP, showing retained binding affinity and no significant conformational changes.
DOI 10.1101/2025.08.24.672003