Gonzalo Ernesto González-Páez

This study characterizes the structure and function of antibodies targeting the conserved β-epitope region of PfCSP, showing how they achieve strain-transcending recognition and enhance Fc-mediated immune responses.

The paper determines the crystal structures of engineered monoclonal antibodies MAM01 and MS-1805 in complex with Plasmodium falciparum CSP, showing retained binding affinity and no significant conformational changes.