Monika Jain

This study identifies potent antimalarial antibodies in African infants vaccinated with RTS,S/AS01E, showing near-germline configurations and protective efficacy.

This study characterizes the structure and function of antibodies targeting the conserved β-epitope region of PfCSP, showing how they achieve strain-transcending recognition and enhance Fc-mediated immune responses.

This study determines the structural basis of antigen recognition by two mAbs targeting PfCSP, revealing conserved and distinct binding modes and their implications for antibody function.

This study uses deep learning to design multi-epitope scaffolds mimicking CSP's spatial structure, showing accurate positioning of two epitopes and partial success with the third.

This study determines the structure of HAstV spikes bound to FcRn, identifies conserved epitopes, and suggests repurposing FcRn inhibitors for antiviral therapy.

The paper determines the crystal structures of engineered monoclonal antibodies MAM01 and MS-1805 in complex with Plasmodium falciparum CSP, showing retained binding affinity and no significant conformational changes.