Author

Xiao Ping Yang

Columbia University Irving Medical CenterORCID 0000-0003-1675-1995Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiao Ping Yang1 paper · Johns Hopkins University

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Bo HuangiD· 1 shared Clay LacefieldiD· 1 shared Emily Sun· 1 shared Gergely F. TuriiD· 1 shared Hongbo ZhangiD· 1 shared Phi T. NguyeniD· 1 shared Qingbo Xu· 1 shared René HeniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Bo HuangORCID

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2 papers

Recent·Most cited

Reactivation of a dormant developmental plasticity program drives synaptic rejuvenation and antidepressant-like responses

Phi T. Nguyen, Emily Sun, Yuecheng Shi, Shogo Tamura, Xiao Ping Yang, Clay Lacefield, Gergely F. Turi, René Hen

This study shows that fluoxetine reactivates a dormant developmental plasticity program in mature neurons, leading to synaptic rejuvenation and antidepressant-like effects.

bioRxiv · Jan 3, 2025 · PreprintNeuroscience

Using macromolecular electron densities to improve the enrichment of active compounds in virtual screening

Wenzhi Ma, Wei Zhang, Yuan Le, Xiaoxuan Shi, Qingbo Xu, Xiao Ping Yang, Yueying Dou, Xiaoman Wang, Wenbiao Zhou, Wei Peng, Hongbo Zhang, Bo Huang

This paper introduces ExptGMS, a method using experimental electron density data to improve virtual screening by enhancing active compound enrichment, achieving a 20% improvement and identifying new inhibitors.

Communications Chemistry · Aug 22, 2023Peer-reviewedBioinformatics