Emily Sun

Scaling Large Language Models for Next-Generation Single-Cell Analysis

This paper scales large language models for single-cell analysis, improving predictive and generative capabilities and enabling biological discovery through virtual screening.

Allosteric inhibition rescues hydrocephalus caused by catalytically inactive Shp2

This study shows that a catalytically inactive Shp2 mutation causes hydrocephalus by altering conformation, which can be rescued by allosteric inhibition.

Reactivation of a dormant developmental plasticity program drives synaptic rejuvenation and antidepressant-like responses

This study shows that fluoxetine reactivates a dormant developmental plasticity program in mature neurons, leading to synaptic rejuvenation and antidepressant-like effects.