Vincent M. Bruno

This study shows that HosA, a histone deacetylase in A. fumigatus, regulates stress resistance, host cell interactions, and virulence by modulating gene expression related to secondary metabolism and energy metabolism.

This paper shows EGFR signaling is essential for host defense against invasive aspergillosis, as its inhibition worsens infection outcomes in immunosuppressed mice.

The paper identifies Als5 and Scf1 as complementary adhesins in Candida auris that promote cell-cell interaction and biofilm formation through functional redundancy.

The paper identifies a false positive in m5C detection by Tombo in GCU motifs across diverse RNA samples, suggesting published findings should be re-evaluated.

The paper compares transcriptome changes in yeast when ribosome formation is inhibited versus ribosome function is inhibited, finding distinct gene expression patterns.

This study evaluates the impact of read length and pairing on differential expression analysis in host-pathogen interactions, finding 54-bp paired reads most robust and 36-bp single reads suitable for bacterial samples.

This study compares enrichment techniques for multi-species RNA-Seq, finding that targeted enrichment with Agilent SureSelect improves read mapping to target organisms.

The paper compares gene expression patterns under ribosomal and translational stress to determine the underlying mechanisms of cell cycle arrest.