Author

Liyuan Zhu

Cardiovascular Research CenterORCID 0000-0003-1702-1118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alan DaughertyiD· 2 shared Deborah A. HowattiD· 2 shared Hong S. LuiD· 2 shared Jessica J. MoorlegheniD· 2 shared Michael FrankliniD· 2 shared Adam E. MullickiD· 1 shared Hisashi SawadaiD· 1 shared Kenneth W. DunniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Alan DaughertyORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintAug 9, 2026

Hepatocyte Angiotensinogen Deletion Protects Against Diet-induced Metabolic Disorders in Mice Under Thermoneutral Conditions

Liyuan Zhu, Michael Franklin, Deborah A. Howatt…·Hong S. Lu

This study shows that deleting angiotensinogen in hepatocytes protects mice from diet-induced metabolic disorders even under thermoneutral conditions that mimic human metabolism.

DOI 10.64898/2026.08.04.742617

mousebulk RNA-seq

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PathologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedNov 21, 2024

Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet

Naofumi Amioka, Michael Franklin, Masayoshi Kukida…·Hong S. Lu

This study shows that deleting megalin in renal proximal tubule cells does not reduce atherosclerosis but causes tubulointerstitial nephritis in male mice fed a Western diet.

5 citations

mouseexperimental assay

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