Masayoshi Kukida

This paper establishes an OTAC mouse model to study medial arterial calcification, identifying osteochondrogenic transdifferentiation of vascular smooth muscle cells and associated microenvironmental changes using scRNA-seq.

This study shows that deleting megalin in renal proximal tubule cells does not reduce atherosclerosis but causes tubulointerstitial nephritis in male mice fed a Western diet.

This study shows that renal angiotensinogen in nonhuman primates is mainly derived from the liver, as evidenced by reduced renal AGT levels after liver-specific AGT inhibition.