Shaliu Fu

AlphaCell simulates perturbation-induced cellular dynamics by addressing limitations in current models through three innovations: latent manifold rectification, biological reality reconstruction, and universal state transition.

This paper benchmarks 40 single-cell multi-modal integration algorithms across paired, unpaired, and mosaic datasets to evaluate usability, accuracy, and robustness.

This study introduces TCRBagger, a weakly-supervised framework for peptide-TCR binding prediction to improve neo-epitope identification in tumor immunotherapy.

scPrivacy enables privacy-preserving integration of single-cell RNA-seq datasets from multiple institutions for cell type identification.