Xingbo Yang

The paper investigates subcellular ETC flux gradients in mouse oocytes and finds that mitochondrial heterogeneity, not oxygen diffusion, drives these gradients.

This study uses control theory to analyze dynamic metabolic responses in mouse oocytes, revealing cytoplasmic NADH flux overshoot due to mitochondrial-cytoplasmic coupling and nutrient partitioning.

AlphaCell simulates perturbation-induced cellular dynamics by addressing limitations in current models through three innovations: latent manifold rectification, biological reality reconstruction, and universal state transition.

This study introduces in vitro assays to quantify actin-binding protein (ABP) activity in actin turnover and identifies conditions that maximize turnover efficiency.