Author

Andrey G. Malyutin

California Institute of TechnologyORCID 0000-0003-1716-5437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron P. McGrathiD· 1 shared Anthony P. WestiD· 1 shared Christopher O. BarnesiD· 1 shared Claudia A. JetteiD· 1 shared Daniel W. CarneyiD· 1 shared Davide F. RobbianiiD· 1 shared Guliang Xia· 1 shared Harry B. GristickiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Aaron P. McGrathORCID

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2 papers

Recent·Most cited

Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands

Zongyang Lyu, Xiaoxuan Lyu, Andrey G. Malyutin, Guliang Xia, Daniel W. Carney, Vinícius M. Alves, Matthew S. Falk, Nidhi Arora, Hua Zou, Aaron P. McGrath, Yanyong Kang

This study presents structural insights into PAR1 and PAR2 activation by endogenous ligands, revealing a novel mechanism and potential targets for therapeutic development.

Nature Communications · Apr 26, 2025Peer-reviewedBiochemistry

Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies

Christopher O. Barnes, Claudia A. Jette, Morgan E. Abernathy, Kim-Marie A. Dam, Shannon R. Esswein, Harry B. Gristick, Andrey G. Malyutin, Naima G. Sharaf, Kathryn E. Huey‐Tubman, Yu Erica Lee, Davide F. Robbiani, Michel C. Nussenzweig, Anthony P. West, Pamela J. Björkman

The paper classifies neutralizing antibodies against SARS-CoV-2 spike RBD based on structure, identifying binding modes and implications for vaccine and therapeutic strategies.

Nature · Oct 12, 2020Peer-reviewedMolecular Biology