Cell BiologyMolecular CellPeer-reviewed
D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability
Gergely Róna, Bearach Miwatani-Minter, Qingyue Zhang…·Michele Pagano
This study shows D-type cyclins inhibit mismatch repair (MMR) in G1 phase by shielding p21, while their degradation in S phase enables proper MMR function, maintaining genome stability.
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