Anca Dorhoi

This study uses spatial transcriptomics to identify a hypoxia-associated SPP1-enriched microenvironment in pediatric TB granulomas that may contribute to incomplete bacterial clearance.

This study compares IFNγ-induced iNOS activity in human and murine tuberculosis models, finding minimal iNOS expression in human myeloid cells and identifying epithelial cells as primary iNOS sources.

This study uses bat epithelial organoids to investigate antiviral immunity differences between bats and humans, revealing unique interferon responses and implications for viral pathogenesis.