Max J. Kellner

Reconstructing bat antiviral immunity using epithelial organoids

This study uses bat epithelial organoids to investigate antiviral immunity differences between bats and humans, revealing unique interferon responses and implications for viral pathogenesis.

Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants

This paper shows that clinical-grade soluble ACE2 effectively inhibits multiple SARS-CoV-2 variants, including VOCs, in cell cultures and across independent labs.

A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing

This paper presents an improved RT-LAMP assay for SARS-CoV-2 detection that is rapid, sensitive, and suitable for both laboratory and home testing.

Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections

The paper shows clinical grade recombinant ACE2 effectively neutralizes SARS-CoV-2 Omicron in VeroE6 cells, outperforming neutralization against reference isolates.

Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites

The paper identifies two lectins, Clec4g and CD209c, that bind to conserved glycosylation sites on SARS-CoV-2 Spike and reduce viral infections.

SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier

This study shows SARS-CoV-2 infects choroid plexus epithelial cells in brain organoids, disrupts the blood-CSF barrier, and may contribute to neurological complications.

MicroRNA Dynamics and Functions During Arabidopsis Embryogenesis

The paper profiles miRNAs and their targets during Arabidopsis embryogenesis, showing their role in regulating transcription factors and embryo morphogenesis.