Author

Matthew August Odenwald

University of ChicagoORCID 0000-0003-1740-6472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Ashley M. SidebottomiD· 2 shared Christopher J. LehmanniD· 2 shared Mary McMilliniD· 2 shared Alexandra M. Clarke· 1 shared Amber R. RoseiD· 1 shared Andrew Brantley HalliD· 1 shared Angela K JiangiD· 1 shared Angelica MoraniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Ashley M. SidebottomORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 8, 2026

SpiE is a distinct gut microbial 4-cholesten-3-one 5β-reductase that acts with SpiR to convert cholesterol to coprostanol

Angela K Jiang, Gabriela Arp, Margaret Kato…·Xiaofang Jiang

The paper identifies SpiE as a gut microbial enzyme that, along with SpiR, converts cholesterol to coprostanol, and shows its correlation with stool coprostanol levels and antibiotic impact.

DOI 10.64898/2026.10.06.757028

humanmetagenomics

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PathologyPLoS ONEPeer-reviewedJan 9, 2026

Fecal Metabolite Quantitation for Rapid Assessment of the Gut Microbiome

Michael W. Mullowney, Angelica Moran, Antonio Hernandez…·Ashley M. Sidebottom

This paper presents a rapid diagnostic test to measure fecal butyrate and deoxycholic acid concentrations as markers of microbiome function, enabling quick identification of patients with microbiome deficiencies.

5 citationstop 4%

metabolomicsexperimental assay

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