Raman Deep Sharma

This paper identifies a Mycobacterium tuberculosis secreted protein that disrupts host snRNP biogenesis, altering RNA splicing and contributing to pathogenesis.

This study shows Mtb induces PPARγ in hepatocytes to create lipid droplets and drug-tolerant environments, contributing to systemic pathogenicity and metabolic impairments during TB infection.

This study identifies a mitochondrial quality control mechanism that reverses phagosome maturation arrest caused by Mycobacterium tuberculosis through RAB7 recruitment and lysosomal targeting.