Three STEPs forward: A trio of unexpected structures of PTPN5
Liliana Guerrero, Ali Ebrahim, Blake T. Riley, Sean Kim, Anthony C. Bishop, Jiaqian Wu, Ye Na Han, Lutz Tautz, D.A. Keedy
This study presents three new crystal structures of STEP (PTPN5) revealing unexpected conformational features and ligand binding events that provide insights for structure-based drug design.
Proteins Structure Function and Bioinformatics · Jul 5, 2025Peer-reviewedBiophysics