Author

Hanneke Vlaming

Harvard UniversityORCID 0000-0003-1743-6428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Claudia A. MimosoiD· 2 shared Karen AdelmaniD· 2 shared Andrew R. FieldiD· 1 shared Benjamin J. E. MartiniD· 1 shared Nathalie P. Vroegindeweij-de WagenaariD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersGenomics

Claudia A. MimosoORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 8, 2025

Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci

Claudia A. Mimoso, Hanneke Vlaming, Nathalie P. Vroegindeweij-de Wagenaar, Karen Adelman

The paper investigates how the Restrictor complex suppresses non-coding RNA transcription by slowing RNA polymerase II elongation, preventing transcriptional interference at divergent promoters.

2 citations

bulk RNA-seqexperimental assay

𝕏 PostBluesky

GenomicsNature Structural & Molecular BiologyPeer-reviewedJun 1, 2022

Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential

Hanneke Vlaming, Claudia A. Mimoso, Andrew R. Field…·Karen Adelman

The paper identifies sequence features that influence RNA polymerase II elongation potential by screening thousands of transcribed regions using INSERT-seq.

49 citations

bulk RNA-seqexperimental assay

𝕏 PostBluesky