Author

Ayeh Sadat Sadr

Institute of Cancer ResearchORCID 0000-0003-1744-9341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:multiome· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alejandra BrunaiD· 2 shared Alejandro Allo AnidoiD· 2 shared Christie English· 2 shared Emilia CheniD· 2 shared Siân HameriD· 2 shared Abigail SheaiD· 1 shared Andrea Michelle Castaneda Moreno· 1 shared Angella Bellini· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Alejandra BrunaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 13, 2025

AP-1 Primes Transcriptional Noise-Led Cancer Treatment Adaptation Through KDM5 Chromatin Rewiring

Alejandro Allo Anido, Cecilia Roux, Ayeh Sadat Sadr…·Alejandra Bruna

The paper identifies transcriptional noise as a driver of cancer treatment adaptation through AP-1 and KDM5-mediated chromatin rewiring in neuroblastoma and hepatoblastoma.

DOI 10.1101/2025.10.13.682004

humanscRNA-seq

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Cancer BiologybioRxivPreprintApr 16, 2025

Integrated Lineage Tracing in Hepatoblastoma Finds a Plasticity-Proliferation Axis Drives Adaptation

Emilia Chen, Christie English, Alejandro Allo Anido…·Alejandra Bruna

This study uses single-cell multiomics to trace clonal and phenotypic dynamics in hepatoblastoma after cisplatin treatment, identifying a plasticity-proliferation axis driven by BIRC5.

DOI 10.1101/2025.04.16.648783

humanscRNA-seq

𝕏 PostBluesky