Ruonan Chen

This study shows that colorectal cancers with different metastatic potential trigger distinct early T cell responses, with non-metastatic tumors inducing cytotoxic T cells and pro-metastatic tumors causing hypoactivated T cells.

The paper investigates how mesenchymal tissue fields self-organize into distinct cartilage and soft tissue compartments through structural relations between cells and supracellular structures, influenced by Wnt signaling from epithelial tissue.