Author

Felix Zirngibl

Humboldt-Universität zu BerlinORCID 0000-0003-1764-4841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelika EggertiD· 1 shared Annette KünkeleiD· 1 shared Anton George HensseniD· 1 shared Casper F. T. van der VeniD· 1 shared Chahrazad Lachiheb· 1 shared Dimitrios L. WagneriD· 1 shared Elias Rodríguez-FosiD· 1 shared Emily Ohlendorf· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Angelika EggertORCID

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Author profile →

1 paper

Recent·Most cited

Personalized CRISPR Knock-In Cytokine Gene Therapy to Remodel the Tumor Microenvironment and Enhance CAR T Cell Therapy in Solid Tumors

Michael Launspach, Julia Macos, Shoaib Afzal, Janik Hohmann, Marc L Appis, Maximilian Pilgram, Stefanie Beez, Emily Ohlendorf, Casper F. T. van der Ven, Chahrazad Lachiheb, Karin Toews, Lena Andersch, Marvin Jens, Felix Zirngibl, Jonas Kath, , Annette Künkele

This paper develops CancerPAM, a bioinformatics pipeline for identifying CRISPR knock-in sites to remodel the tumor microenvironment, enhancing CAR T cell therapy in solid tumors.

Nature Communications · Dec 9, 2025Peer-reviewedBioengineering