Author

Dawn Qingqing Chong

National Cancer Centre SingaporeORCID 0000-0002-9635-1344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant calling· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Iain Beehuat TaniD· 3 shared Anna GaniD· 2 shared Polly S. Y. PooniD· 2 shared Pui‐Mun WongiD· 2 shared Sarah Boon Hsi NgiD· 2 shared Yi Ting LauiD· 2 shared Ahmed Abdelmoneim· 1 shared Aik Yong ChokiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Iain Beehuat TanORCID

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3 papers

Recent·Most cited

Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles

Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty, Denis Odinokov, Probhonjon Baruah, Hanaé Carrié, Avril Joy Lim, Yu Amanda Guo, Zhong Wee Poh, Ngak Leng Sim, Ahmed Abdelmoneim, Yutong Cai, Lakshmi Narayanan Lakshmanan, Danliang Ho, Saranya Thangaraju, , Anders J. Skanderup

Fragle quantifies ctDNA from fragment length profiles using deep learning, showing high accuracy and improved detection limits across multiple datasets and sequencing types.

bioRxiv · Jul 28, 2023 · PreprintBioinformatics

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

Peh Joo Ho, Iain Beehuat Tan, Dawn Qingqing Chong, Chiea Chuen Khor, Jian‐Min Yuan, Woon‐Puay Koh, Rajkumar Dorajoo, Jingmei Li

This paper evaluates polygenic risk scores for predicting common cancers in East Asians using a large cohort, finding significant risk stratification for breast, prostate, and colorectal cancers.

eLife · Mar 27, 2023Peer-reviewedGenetic & Genomic Medicine

Heatrich-BS enables efficient CpG enrichment and highly scalable cell-free DNA methylation profiling

Elsie Cheruba, Ramya Viswanathan, Pui‐Mun Wong, Howard John Womersley, Yi Ting Lau, Anna Gan, Polly S. Y. Poon, Sarah Boon Hsi Ng, Dawn Qingqing Chong, Iain Beehuat Tan, Lih Feng Cheow

bioRxiv · Apr 5, 2021 · PreprintGenomics