MicrobiologybioRxivPreprint
Intrinsic flexibility of Type VII secretion central pore is required for substrate translocation
Christina Ritter, Katherine S. H. Beckham, Grzegorz Chojnowski…·Matthias Wilmanns
This study shows that the flexibility of the central pore in the ESX-5 type VII secretion system is essential for efficient substrate translocation, as rigidification of key residues impairs secretion.
DOI 10.64898/2026.07.31.742005