EGFR-targeted affibody-polyIC polyplex kills EGFR-overexpressing cancer cells without activating the EGFR
Anne Pettikiriarachchi, Yelena Ugolev, Richard W. Birkinshaw…·Alexander Levitzki
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The University of MelbourneORCID 0000-0003-1825-0182Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Anne Pettikiriarachchi, Yelena Ugolev, Richard W. Birkinshaw…·Alexander Levitzki
Alexandra D. Gurzau, Richard W. Birkinshaw, Andrew P. Leis…·Marnie E. Blewitt
This study identifies a second DNA-binding site in SMCHD1 and shows that DNA binding stimulates its ATPase activity, revealing a mechanism for gene silencing.
Kaiming Li, Yu Q. Yap, Donia M. Moujalled…·Guillaume Lessène
This study identifies a small molecule that differentially regulates BAX and BAK apoptotic activity by modulating their interaction with VDAC2, revealing therapeutic potential for overcoming drug resistance in leukemia.