Author
Broad InstituteORCID 0000-0002-4521-0568Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kannan Vrindavan Manian, Connor Ludwig, Yan Zhao…·Jason Comander
The paper presents a high-resolution map of RHO missense variants' trafficking and evaluates pharmacologic correction with YC-001, identifying pathogenic variants and therapeutic potential.
Conor J Howard, Nathan S. Abell, Robert Warneford-Thomson…·Diane E. Dickel
This study uses deep mutational scanning to analyze TYK2 variants and their impact on function and drug response, identifying novel therapeutic targets and degradation strategies.
Ozgur Oksuz, Jonathan E. Henninger, Robert Warneford-Thomson…·Richard A. Young
The paper identifies RNA-binding as a common feature of transcription factors, showing it contributes to gene regulation and is conserved in vertebrates.