Author
University Hospital LeipzigORCID 0000-0003-1863-3239Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Manja Wobus, Heike Weidner, Rebekka Wehner…·Katja Sockel
This study evaluates tasquinimod's efficacy in MDS by showing it reduces inflammation, improves erythropoiesis, and enhances bone health in a mouse model.
Angelique Schönefeld, Costanza Zanetti, Eric C. Schmitt…·Borhane Guezguez
This study shows that inhibiting the DNMT/G9a complex targets specific epigenetic vulnerabilities in AML, inducing an IFN response and improving therapeutic outcomes.
Cornelius Pauli, Michael Kienhöfer, Maximilian Felix Blank…·Michaela Frye
The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.
Elsa Bernard, Yasuhito Nannya, Robert Paul Hasserjian…·Elli Papaemmanuil
The paper examines TP53 allelic states in MDS patients, finding that bi-allelic targeting is linked to worse outcomes, while mono-allelic targeting does not differ from wild-type patients.