Author
German Cancer Research CenterORCID 0000-0002-5636-6840Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Stefania Prete, Yoav Avi-Guy, Fu Xu, Sabrina Weser, Milica Bekavac, Marie-Luise Koch, Francesca Coraggio, Raphael T. F. Coimbra, Martyna C. Popis, Anke Heit-Mondrzyk, Ângela Gonçalves, Mikaela Behm, Duncan T. Odom, Michaela Frye
This study tracks somatic mutation evolution in hair follicles to forecast early skin cancer development non-invasively.
bioRxiv · Sep 1, 2026 · PreprintCell Biology
Chia Ching Wu, Isabel S. Naarmann‐de Vries, Jonas Hartmann, Zarina Nidoieva, Kevin Kopietz, Virginie Marchand, Zeynep Özrendeci, Doris Lindner, Sophia Schelchshorn, Sophia Flad, Michaela Frye, Fotini Nina Papavasiliou, Tanja Schirmeister, Georg Stoecklin, Johanna Schott, , Alessia Ruggieri
ViREn is a two-step method that purifies dengue virus RNA with high purity, revealing a 5-methylcytosine modification mediated by NSUN6 that affects RNA turnover.
Nucleic Acids Research · Jan 7, 2026Peer-reviewedBiochemistry
Milica Bekavac, Raphael T. F. Coimbra, Veronica F. Busa, Mikaela Behm, Rebecca E. Wagner, Ângela Gonçalves, Sabine Begall, Michaela Frye, Duncan T. Odom
The paper presents a high-quality de novo genome assembly of Ansells mole-rat using long-read, short-read, and Hi-C data, enabling genetic and phylogenetic studies.
G3 Genes Genomes Genetics · Nov 11, 2025Peer-reviewedGenomics
Rebecca E. Wagner, Leonie Arnetzl, Thiago Britto‐Borges, Anke Heit-Mondrzyk, Ali Bakr, Etienne Sollier, Nikoletta A. Gkatza, Jasper Panten, Sylvain Delaunay, Daniela Sohn, Peter Schmezer, Duncan T. Odom, Karin Müller‐Decker, Christoph Plass, Christoph Dieterich, , Michaela Frye
This study shows that SRSF2 mutations cause DNA damage and cell cycle arrest, highlighting its role in transcription regulation during cell division.
Cell Reports · Oct 23, 2024Peer-reviewedCell Biology
Cornelius Pauli, Michael Kienhöfer, Maximilian Felix Blank, Oguzhan Begik, Christian Rohde, Daniel Heid, Fu Yong Xu, Sarah Miriam Naomi Zimmermann, Katharina Weidenauer, Sylvain Delaunay, Nadja Krall, Katrin Trunk, Duoduo Zhao, Fengbiao Zhou, Anke Heit-Mondrzyk, , Michaela Frye
The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.
bioRxiv · Jul 13, 2024 · PreprintCell Biology
Tommaso Selmi, Shobbir Hussain, Sabine Dietmann, Matthias Heiß, Kayla M. Borland, Sophia Flad, Jean-Michel Carter, Rebecca A. Dennison, Ya‐Lin Huang, Stefanie M. Kellner, Susanne Bornelöv, Michaela Frye
The paper identifies NSUN6 as a methyltransferase that specifically targets mRNA 3UTR regions with the CTCCA motif, affecting translation termination but not essential for mouse development.
Nucleic Acids Research · Nov 24, 2020Peer-reviewedMolecular Biology