Author

Tian Wang

University of ArizonaORCID 0000-0003-1867-5850Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Tian Wang4 papers · University of Southern California

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:imaging· 1 Assay:metabolomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Roberta Dı́az BrintoniD· 2 shared Adam C. RaikesiD· 1 shared Avnish BhattraiiD· 1 shared Fei YiniD· 1 shared Jean‐Paul L. WiegandiD· 1 shared John W. McLean· 1 shared Yuan Shang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersNeuroscience

Roberta Dı́az BrintonORCID

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2 papers

Recent·Most cited

NeuroscienceFrontiers in NeurosciencePeer-reviewedJul 14, 2026

Humanized APOE mouse brain volume increases over age irrespective of sex and APOE genotype: Implications for translational validity to the human

Adam C. Raikes, Avnish Bhattrai, Tian Wang…·Roberta Dı́az Brinton

The paper analyzes brain volume changes in humanized APOE mice across age and genotype, finding age-related increases in total brain volume and no significant sex or genotype differences in localized volume changes.

2 citationstop 4%

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NeuroscienceFrontiers in Aging NeurosciencePeer-reviewedJun 2, 2026

APOE4 Accelerates Menopause-Associated Brain Metabolic Shift and Disrupts Bioenergetic Adaptation

Tian Wang, Yuan Shang, John W. McLean…·Roberta Dı́az Brinton

This study shows that APOE4 accelerates menopause-related metabolic decline and impairs bioenergetic adaptation in the brain, increasing Alzheimer's disease risk.

1 citation

mousemetabolomics

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