Sarah E. Zanders

Fission yeast Fss1, a PQ-loop membrane protein, acts in diploids to build full-thickness, chitin-containing spore walls and within spores to maintain vacuole morphology and timely germination.

The paper investigates how pericentromeric repeat copy number affects chromosome segregation and gene expression in fission yeast by analyzing natural variation and engineered strains.

This study examines how stress and aging affect spore health in Schizosaccharomyces pombe, identifying declines in germination, asymmetry, and stress tolerance.

This paper uses saturation transposon mutagenesis to identify essential genes and drug resistance mechanisms in Cryptococcus neoformans.

This study investigates the molecular mechanisms of wtf killer meiotic drivers in fission yeasts, identifying factors that constrain toxicity and neutralization, and suggests potential roles in infertility.

The paper investigates how wtf4 meiotic drivers in S. pombe use dual transcriptional regulation and selective protein exclusion to ensure their transmission through gametes.

This paper identifies 532 genes involved in sexual reproduction in fission yeast using transposon-insertion sequencing, including 200 previously uncharacterized genes with vertebrate orthologs.

The paper functionally characterizes 22 additional wtf genes in S. pombe, identifying eight new meiotic drivers and three new suppressors, showing high gamete-killing efficiency despite sequence divergence.