Victoria E. Johnson

This study develops an in vivo model of human traumatic brain injury using human cortical organoids transplanted into rats, showing injury progression and neuroinflammatory responses.

PIGMENT is a deep learning framework that automates the segmentation and quantification of APP-positive pathology in porcine white matter histology, achieving high detection rates with limited expert annotations.

This study investigates changes in hippocampal oscillations after TBI, finding disrupted theta-gamma coupling and altered spike-field coherence in injured rats.

This study shows that T-cell infiltration persists chronically in the brain after focal cortical contusion in swine, but not with inertial injury, suggesting an adaptive immune response to TBI.

This study examines electrophysiological changes in hippocampal neurons and their subtypes in a porcine model of concussion, finding altered properties in interneurons and hyperexcitability in pyramidal neurons.

This study evaluates multichannel silicon probes for chronic electrophysiological recordings in large animals, finding that probe cross-sectional area and design affect single-unit performance and long-term viability.

The paper characterizes the laminar structure of the porcine hippocampus using histology and electrophysiology, finding features similar to both rodents and primates.