Florian Full

This study shows HSV infection increases ALS risk and promotes TDP-43 pathology through ICP0-mediated disruption of PML bodies.

This study investigates the cellular response to poxvirus infection, showing that MVA activates innate immune genes, while Camelpoxvirus activates NF-kB signaling, and poxviruses induce nuclear remodeling by transporting nuclear proteins into viral factories.

This study shows DNA virus infections activate transposable elements (TEs) through KAP1/TRIM28 inhibition and DUX4 expression, with in vivo correlations in cancer patients.

The paper identifies CRNKL1 as a regulator that enhances nuclear retention of intron-retaining HIV-1 and cellular mRNAs, affecting their cytoplasmic levels.