Karin M. Danzer

This study investigates how aging and α-synuclein pathology affect glucocorticoid sensitivity in splenocytes, finding reduced sensitivity in aged mice and PD models at specific ages.

The paper shows that CASIN inhibits CDC42, reversing PD-related transcriptional changes and affecting MAPK and PI3K/AKT pathways in an aging mouse model.

This study shows HSV infection increases ALS risk and promotes TDP-43 pathology through ICP0-mediated disruption of PML bodies.

The paper shows that loss of FXR1 and FXR2 leads to TDP-43 accumulation in stress granules, linking FXP family reduction to neurodegenerative pathology.

This study shows that aging processes drive Parkinson's Disease in a mouse model, independent of alpha-synuclein oligomers, by targeting CDC42 activity.

The paper identifies a monocyte dysregulation signature in MDD linked to clinical symptoms using CITE-Seq data from PBMCs.

The paper investigates how alpha-synuclein oligomers spread in a mouse model of Parkinson's disease, identifying age-related astrocyte changes and dysfunction in the astrocyte-glutamatergic neuron system.

This study uses patient-derived organoids to predict drug response and track tumor evolution in pancreatic cancer.