J. Christof M. Gebhardt

The paper investigates the distinct roles of SRCAP and H2A.Z in gene regulation during the cell cycle in pluripotent stem cells, revealing SRCAP's H2A.Z-independent inhibitory function and H2A.Z's repressive role in lineage-specific gene expression.

CaiNet simulates gene regulatory networks with stochastic molecular kinetics and infers steady-state network structure from measurements.

The paper shows that mitotic chromosome binding of transcription factors correlates with their interphase properties and impact on chromatin accessibility.