Author

Andrea Brigitta Alber

Boston UniversityORCID 0000-0001-6183-7208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Darrell N. KottoniD· 3 shared Brigitte N. GompertsiD· 2 shared Cédric DeluziD· 2 shared Chandani SeniD· 2 shared David M. SuteriD· 2 shared Elias T. FrimaniD· 2 shared George KwongiD· 2 shared Konstantinos–Dionysios AlysandratosiD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Darrell N. KottonORCID

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Author profile →

5 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 25, 2026

Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis

Chandani Sen, Justin Langerman, Konstantinos–Dionysios Alysandratos…·Brigitte N. Gomperts

This study develops a 3D co-culture organoid model of IPF to investigate epithelial-fibroblast interactions and test anti-fibrotic drugs.

DOI 10.64898/2026.01.29.702646

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Molecular BiologybioRxivPreprintJan 31, 2026

Bidirectional fibrogenic cross-talk revealed in a human iPSC-derived epithelial-mesenchymal co-culture model of pulmonary fibrosis

Andrea Brigitta Alber, George Kwong, Vishal K Gupta…·Darrell N. Kotton

The paper establishes a human iPSC-derived co-culture model of pulmonary fibrosis that reveals bidirectional fibrogenic epithelial-mesenchymal crosstalk and identifies potential druggable pathways.

2 citations

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Developmental BiologyNature CommunicationsPeer-reviewedJun 13, 2023

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme

Andrea Brigitta Alber, Hector A. Marquez, Liang Ma…·Darrell N. Kotton

This study generates lung-specific mesenchyme from mouse iPSCs, identifies key signaling pathways, and demonstrates functional interactions with lung epithelial progenitors.

30 citations

mouseexperimental assay

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Developmental BiologyMolecular Systems BiologyPeer-reviewedSep 1, 2019

Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

Daniel Strebinger, Cédric Deluz, Elias T. Friman…·David M. Suter

The paper shows that fluctuations in OCT4 and SOX2 levels influence cell fate decisions by affecting chromatin accessibility at differentiation enhancers.

88 citations

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GenomicsNature CommunicationsPeer-reviewedJan 30, 2019

Mitotic chromosome binding predicts transcription factor properties in interphase

Mahé Raccaud, Elias T. Friman, Andrea Brigitta Alber…·David M. Suter

The paper shows that mitotic chromosome binding of transcription factors correlates with their interphase properties and impact on chromatin accessibility.

98 citationstop 4%

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