Maurits Unkel

This study benchmarks clustering methods for high-dimensional spike time-window data from MEAs, finding that PCA with k-means and Euclidean distance performs best.

This paper introduces a method to generate adherent cortical organoids in a multiwell format, showing reproducible 3D cortical layer formation and potential for drug discovery and disease modeling.

This study develops a method to differentiate human pluripotent stem cells into functional astrocytes in 28 days, validated by marker expression and network activity support.

The paper identifies a minimum threshold for myelination of pyramidal neurons' axons in human and mouse neocortex based on axonal calibre and interbranch distance.