Author

Matthew P. Edgington

The Pirbright InstituteORCID 0000-0003-1922-9529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Luke AlpheyiD· 2 shared Alexander Dodds· 1 shared Estela GonzáleziD· 1 shared Eunice O. AdedejiiD· 1 shared Jack Aked· 1 shared Jake CreaseyiD· 1 shared James C. Y. Luk· 1 shared Joshua Southworth· 1 shared

Activity by Year

2019-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Luke AlpheyORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 15, 2025

Integrating multiplexing into confineable gene drives effectively overrides resistance in Anopheles stephensi

Mireia Larrosa‐Godall, Lewis Shackleford, Matthew P. Edgington…·Luke Alphey

The paper assesses two multiplexing strategies for CRISPR/Cas9-based gene drives in Anopheles stephensi to overcome target site resistance.

1 citation

experimental assay

𝕏 PostBluesky

Synthetic BiologyJournal of Theoretical BiologyPeer-reviewedJun 28, 2019

Modeling the mutation and reversal of engineered underdominance gene drives

Matthew P. Edgington, Luke Alphey

This paper models mutation and reversal of engineered underdominance gene drives, showing mutations can break them and free suppressors are less effective than wild-type releases for reversal.

16 citations

statistical model

𝕏 PostBluesky