Author

Anup Aggarwal

St. Jude Children's Research HospitalORCID 0000-0003-1937-964XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Anand Mayasundari· 2 shared Gisele NishiguchiiD· 2 shared Lei YangiD· 2 shared Marisa Actis· 2 shared Zoran RankovićiD· 2 shared Anastasia Bednarz· 1 shared Angelina Li· 1 shared Bachuki ShashikadzeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Anand Mayasundari

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 20, 2025

✦ In-depth digest

Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics

Martin Steger, Gisele Nishiguchi, Qiong Wu…·Zoran Ranković

Proteomics and ubiquitinomics screening of 100 CRBN ligands in two cell lines validated 50 novel neosubstrates and yielded selective phenyl glutarimide degraders of KDM4B, G3BP2 and VCL.

40 citationstop 1%

humanproteomics

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Cancer BiologybioRxivPreprintJul 3, 2025

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia

Jun J Yang, Gisele Nishiguchi, Satoshi Yoshimura…·Marcus M. Fischer

This study develops LCK-targeting molecular glues that overcome resistance to kinase inhibitors in T-ALL by inducing CRBN-dependent degradation of LCK.

1 citation

humanproteomics

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