Author
Bachuki Shashikadze
Ludwig-Maximilians-Universität MünchenORCID 0000-0003-4558-0785Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links5 papers
Recent·Most cited
- BiochemistrybioRxivPreprint
Discovery of CDK4-selective molecular glue degraders by high-throughput proteomics
Patrick R. A. Zanon, Bachuki Shashikadze, Denise Winkler…·Henrik Daub
This study identifies a CDK4-selective molecular glue degrader, NE26394, using high-throughput proteomics, showing its efficacy in CDK4-dependent cancer models.
DOI 10.64898/2026.06.19.733443 - BiochemistrybioRxivPreprint
Integrated proteomic screening reveals design principles of CRBN molecular glue degraders
Bachuki Shashikadze, Ines F. Scheller, Denise Winkler…·Martin Steger
The paper identifies new CRBN neosubstrates using proteomic screening and machine learning, expanding the landscape of molecular glue degraders.
4 citations - Cancer BiologybioRxivPreprint
Developing Potent and Selective TBK1 Molecular Glue Degraders for Cancer Immunotherapy
John Caldwell, Patrick R. A. Zanon, Iona Ferguson…·Zoran Ranković
This paper develops a first-in-class TBK1 molecular glue degrader, CCT412020, which enhances anti-tumour immunity and overcomes immune checkpoint blockade resistance.
2 citations - BiochemistryNature CommunicationsPeer-reviewed✦ In-depth digest
Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics
Martin Steger, Gisele Nishiguchi, Qiong Wu…·Zoran Ranković
Proteomics and ubiquitinomics screening of 100 CRBN ligands in two cell lines validated 50 novel neosubstrates and yielded selective phenyl glutarimide degraders of KDM4B, G3BP2 and VCL.
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