Judit Gal Toth

This study shows that reducing LINE-1 RNA in hippocampal neurons increases their firing capacity and expands neuronal ensembles, improving spatial memory but reducing pattern separation.

The paper identifies epigenomic and transcriptomic changes in the ventral dentate gyrus of mice exposed to prenatal adversity, linking these changes to anxiety-like behavior.

The paper identifies epigenetically bistable DNA methylation regions in hippocampal granule cells that are linked to behavioral adaptation to environmental changes.

The paper identifies epigenetically bistable regions in neuronal genes that influence neuronal eligibility for coding ensembles in the hippocampus, showing their role in spatial memory and excitability.