Miklós Tóth

This study shows that reducing LINE-1 RNA in hippocampal neurons increases their firing capacity and expands neuronal ensembles, improving spatial memory but reducing pattern separation.

This study shows cocaine self-administration causes large-scale DNA methylation changes and upregulation of extracellular matrix genes in the dorsal dentate gyrus of mice.

This study shows that drug-context memory acquisition and extinction in mice involve distinct epigenetic and transcriptional changes in the dentate gyrus, with non-overlapping genomic regions and gene functions.

This study identifies PGBD5 as a transposase-derived gene essential for brain development in humans and mice, with deficiency causing intellectual disability and seizures.

The paper identifies epigenomic and transcriptomic changes in the ventral dentate gyrus of mice exposed to prenatal adversity, linking these changes to anxiety-like behavior.

The paper identifies epigenetically bistable DNA methylation regions in hippocampal granule cells that are linked to behavioral adaptation to environmental changes.

The paper identifies epigenetically bistable regions in neuronal genes that influence neuronal eligibility for coding ensembles in the hippocampus, showing their role in spatial memory and excitability.

This study shows that NMD regulates synaptic plasticity and cognitive function by controlling GluR1 levels through local mRNA degradation and synthesis in dendrites.