Peter U. Hámor

Expanding Hippocampal Ensembles through LINE-1 RNA Downregulation Enhances Cognition

This study shows that reducing LINE-1 RNA in hippocampal neurons increases their firing capacity and expands neuronal ensembles, improving spatial memory but reducing pattern separation.

Prenatal adversity configures a subpopulation of ventral dentate granule cells for recruitment to drive innate anxiety

The paper identifies epigenomic and transcriptomic changes in the ventral dentate gyrus of mice exposed to prenatal adversity, linking these changes to anxiety-like behavior.

Morphine-context associative memory and locomotor sensitization in mice are modulated by sex and context in a dose-dependent manner

This study examines how morphine's effects on locomotor sensitization and context association differ between male and female mice, showing sex-dependent dose-related changes in behavior and memory.

Rapid nongenomic estrogen signaling controls alcohol drinking behavior

This study shows that high estrogen levels during the proestrus phase increase binge drinking in female mice via rapid nongenomic signaling at estrogen receptor alpha in the bed nucleus of the stria terminalis.

Valence and salience encoding by parallel circuits from the paraventricular thalamus to the nucleus accumbens

This study identifies two parallel circuits from the paraventricular thalamus to the nucleus accumbens that encode valence and salience with sex-dependent differences.

Ceftriaxone and mGlu2/3 interactions in the nucleus accumbens core affect the reinstatement of cocaine-seeking in male and female rats

This study shows ceftriaxone reduces cocaine-seeking by interacting with mGlu2/3 receptors in the nucleus accumbens core, as blocking these receptors prevents ceftriaxone's effect.

The divergent effects of CDPPB and cannabidiol on fear extinction and anxiety in a predator scent stress model of PTSD in rats.

This study tests CDPPB and CBD on fear extinction and anxiety in a PTSD rat model, finding CDPPB enhances extinction without increasing anxiety, while CBD reduces anxiety in susceptible rats.