NeuroscienceCell Death and DiseasePeer-reviewed
Rescue of the increased susceptibility to Mild Chronic Oxidative Stress of iNeurons carrying the MAPT Chromosome 17q21.3 H1/H1 risk allele by FDA-approved compounds
Eldem Sadikoglou, Daniel Domingo‐Fernándéz, Natalia Savytska…·Peter Heutink
The paper investigates how the H1/H1 risk allele at the MAPT locus increases susceptibility to mild chronic oxidative stress in iNeurons and identifies FDA-approved compounds that rescue this vulnerability.
DOI 10.1038/s41419-025-08147-1