Stacy A. Hussong

This study shows that mTOR inhibition restores RNA-regulatory proteins in AD models, suggesting a reversible mTOR-dependent RNA regulatory program in cerebrovascular dysfunction.

This study shows that soluble pathogenic tau aggregates are transmitted to astrocytes, causing mitochondrial dysfunction, senescence, and neurovascular uncoupling in a tauopathy model.

This study shows that mTOR inhibition reduces cerebrovascular Aβ accumulation and improves cognitive function in a mouse model of Alzheimer's disease with cerebral amyloid angiopathy.