Author

Lauren R. Miller

The University of Texas at San Antonio Health Science CenterORCID 0000-0003-0460-6774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Haneen MakhloufiD· 2 shared Stacy A. HussongiD· 2 shared Stephen F. HernandeziD· 2 shared Verónica GalvániD· 2 shared Aishwarya Muppala· 1 shared Angela O. DorigattiiD· 1 shared Candice E. Van SkikeiD· 1 shared Deborah M. HolsteiniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersNeuroscience

Haneen MakhloufORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 14, 2026

Soluble pathogenic tau transmission to astrocytes drives acute oxidative damage, cellular senescence, and neurovascular uncoupling in a model of Alzheimers tauopathy

Haneen Makhlouf, Angela O. Dorigatti, Stephen F. Hernandez…·Verónica Galván

This study shows that soluble pathogenic tau aggregates are transmitted to astrocytes, causing mitochondrial dysfunction, senescence, and neurovascular uncoupling in a tauopathy model.

DOI 10.64898/2026.09.08.750215

mousebulk RNA-seq

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NeurosciencebioRxivPreprintSep 7, 2026

mTOR drives cerebrovascular dysfunction and blood-brain barrier breakdown in a model of Alzheimers disease with cerebral amyloid angiopathy

Candice E. Van Skike, Lauren R. Miller, Stephen F. Hernandez…·Verónica Galván

This study shows that mTOR inhibition reduces cerebrovascular Aβ accumulation and improves cognitive function in a mouse model of Alzheimer's disease with cerebral amyloid angiopathy.

DOI 10.64898/2026.06.23.733858

mouseexperimental assay

𝕏 PostBluesky