Author

Angela O. Dorigatti

Illumina (United States)ORCID 0000-0002-8631-4726Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Deborah M. HolsteiniD· 1 shared Haneen MakhloufiD· 1 shared James Donald LechleiteriD· 1 shared Lauren R. MilleriD· 1 shared Nicholas de Rosa· 1 shared Rakez KayediD· 1 shared Sreemathi LoganiD· 1 shared Stacy A. HussongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Deborah M. HolsteinORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintSep 14, 2026

Soluble pathogenic tau transmission to astrocytes drives acute oxidative damage, cellular senescence, and neurovascular uncoupling in a model of Alzheimers tauopathy

Haneen Makhlouf, Angela O. Dorigatti, Stephen F. Hernandez…·Verónica Galván

This study shows that soluble pathogenic tau aggregates are transmitted to astrocytes, causing mitochondrial dysfunction, senescence, and neurovascular uncoupling in a tauopathy model.

DOI 10.64898/2026.09.08.750215

mousebulk RNA-seq

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