Author

Iryna O. Fedko

Amsterdam Public HealthORCID 0000-0003-1962-916XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 4 Organism:human· 4 Approach:statistical model· 3 Assay:GWAS summary statistics· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Jouke‐Jan HottengaiD· 3 shared Anouk den BraberiD· 2 shared Dorret Irene BoomsmaiD· 2 shared Inga ProkopenkoiD· 2 shared Michel Guillaume NivardiD· 2 shared Aaron L. GoldmaniD· 1 shared Abdel AbdellaouiiD· 1 shared Allan R LinnebergiD· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersGenetics

Jouke‐Jan HottengaORCID

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4 papers

Recent·Most cited

GeneticsSciencePeer-reviewedMar 19, 2020

The genetic architecture of the human cerebral cortex

Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter…·Yuri Milaneschi

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.

875 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 11, 2019

The genomic architecture of blood metabolites based on a decade of genome-wide analyses

Fiona A. Hagenbeek, René Pool, Jenny van Dongen…·Dorret Irene Boomsma

This study estimates heritability and genetic contributions to metabolite levels using genome-wide data and twin-family cohorts, revealing class-specific genetic influences.

1 citation

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsNature GeneticsPeer-reviewedJun 28, 2019

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Sílvia Bonàs‐Guarch, Inês Cebola…·Jorge P. Ferrer

The paper links diabetes-associated enhancers with their target genes using 3D chromatin architecture in human pancreatic islets, revealing genetic variants that impact insulin secretion heritability.

282 citationstop 1%

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 28, 2018

Genetics of fasting indices of glucose homeostasis using GWIS unravels tight relationships with inflammatory markers

Iryna O. Fedko, Michel Guillaume Nivard, Jouke‐Jan Hottenga…·Dorret Irene Boomsma

The paper uses GWIS to analyze genetic correlations between HOMA-B/-IR and inflammatory markers, identifying novel loci and strong genetic links with PAI-1 and C-reactive protein.

2 citations

humanGWAS summary statistics

𝕏 PostBluesky