Manju Kumari

This study shows cardiomyocytes use GBP5 to regulate both pro- and anti-inflammatory responses to IFNγ through the AIM2/CASP1 pathway and GBP5/TGFβ axis.

This study shows that reverse cardiac remodeling is a constrained multicellular state with partial recovery of metabolic programs but persistent inflammatory-mitochondrial dysfunction, mediated by lymphatic-derived Reelin.

This study identifies TRIM24 as a chromatin regulator that suppresses inflammatory signaling in cardiomyocytes, preventing cardiac inflammation and heart failure progression.