Anushka Deshpande

This study identifies TRIM11 as a regulator of EWSR1::ATF1 stability in clear cell sarcoma, showing its depletion leads to metabolic rewiring and cell death, with PCK1 as a potential biomarker.

This study shows that reverse cardiac remodeling is a constrained multicellular state with partial recovery of metabolic programs but persistent inflammatory-mitochondrial dysfunction, mediated by lymphatic-derived Reelin.

This study identifies TRIM24 as a chromatin regulator that suppresses inflammatory signaling in cardiomyocytes, preventing cardiac inflammation and heart failure progression.

This study investigates ZEB1's role in cardiomyocyte structure and function, finding that its deletion causes sarcomere damage, mitochondrial dysfunction, and dedifferentiation, particularly in females.