Qian Yang

This study develops a membrane-anchored influenza neuraminidase vaccine that elicits human-like broadly protective B cell responses and cross-inhibitory activity against diverse NA variants.

The paper identifies broad NA-reactive B cell clones and their clonal evolution, revealing molecular features and inhibitory activity against diverse influenza NAs.

This paper reports on a phase 1 trial of vesemnogene lantuparvovec, an affordable gene therapy for SMA, showing safety and improved motor milestones in young children.

Treatment with eEF2K inhibitors and genetic eEF2K knockout improved cognitive deficits in Alzheimer's disease model mice.